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The broad substrate specificity of GSTs allows them to protectcells against a range of toxic chemicals, however this GST activity can be deleterious incertain cases, as it can contribute to chemoresistance against anti-neoplastic agents in thetreatment of cancer or the arisen metabolite can be more toxic than the primary molecule.Regarding their function within oxidative stress, GSTs detoxify also endogenous unsaturatedaldehydes, epoxides and hydrogen peroxides arisen as the secondary metabolites generatedduring oxidation of membranes or other cellular constituents and thus protect cells fromperoxide-induced cell death. Family members decide as agroup on the most appropriatetime and place to listen to theperpetrator’s request forforgiveness

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The medical condi-tion that resulted in the referral may not be the sole reason for physical therapy. The key conclusions were that theimpact of IDS is limited even in the tiniest infantsbut must be taken into account when choosingVG settings

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